Thomas G Brott Selected Research

Endarterectomy (Thromboendarterectomy)

1/2022	Treatment of carotid stenosis in asymptomatic, nonoctogenarian, standard risk patients with stenting versus endarterectomy trials.
1/2022	Lessons From ACST-2.
1/2021	Editor's Choice - Risk of Stroke before Revascularisation in Patients with Symptomatic Carotid Stenosis: A Pooled Analysis of Randomised Controlled Trials.
1/2021	Absence of Consistent Sex Differences in Outcomes From Symptomatic Carotid Endarterectomy and Stenting Randomized Trials.
1/2019	Secular Trends in Procedural Stroke or Death Risks of Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis.
1/2019	Influence of multiple stents on periprocedural stroke after carotid artery stenting in the Carotid Revascularization Endarterectomy versus Stent Trial (CREST).
1/2019	Long-term outcomes of stenting and endarterectomy for symptomatic carotid stenosis: a preplanned pooled analysis of individual patient data.
1/2019	Safety of Carotid Revascularization in Patients With a History of Coronary Heart Disease.
11/2018	Immediate and Delayed Procedural Stroke or Death in Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis.
11/2018	Periprocedural Stroke and Myocardial Infarction as Risks for Long-Term Mortality in CREST.

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Thomas G Brott Research Topics

Disease

58	Stroke (Strokes) 01/2022 - 07/2001
32	Carotid Stenosis (Carotid Artery Stenosis) 01/2022 - 07/2007
21	Ischemic Stroke 03/2021 - 05/2002
15	Myocardial Infarction 01/2021 - 04/2009
11	Pathologic Constriction (Stenosis) 12/2019 - 07/2001
6	Atherosclerosis 01/2013 - 02/2011
5	Intracranial Hemorrhages (Intracranial Hemorrhage) 03/2021 - 06/2002
5	Hypertension (High Blood Pressure) 12/2020 - 07/2011
5	Ischemia 10/2014 - 09/2005
4	Hemorrhage 03/2021 - 12/2004
2	CADASIL 12/2020 - 01/2013
2	Hemorrhagic Stroke 08/2019 - 10/2014
2	Dyslipidemias (Dyslipidemia) 01/2019 - 10/2015
2	Chest Pain (Chest Pains) 07/2016 - 06/2011
2	Cerebral Hemorrhage 03/2013 - 03/2006
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 07/2011 - 04/2007
2	Hematoma 01/2008 - 12/2004
2	Aneurysm (Aneurysms) 11/2002 - 11/2002
2	Vascular Malformations 11/2002 - 11/2002
2	Wounds and Injuries (Trauma) 11/2002 - 11/2002
1	Transient Ischemic Attack 03/2021
1	Brain Injuries (Brain Injury) 11/2020
1	Atrial Fibrillation 08/2019
1	Cognitive Dysfunction 01/2019
1	Inflammation (Inflammations) 01/2019
1	Coronary Disease (Coronary Heart Disease) 01/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2018
1	Diabetes Mellitus 10/2015
1	Cranial Nerve Injuries 05/2015
1	Carotid Artery Diseases 01/2014
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 07/2011
1	Subdural Hematoma (Subdural Hemorrhage) 01/2008
1	Edema (Dropsy) 03/2006
1	Brain Ischemia (Cerebral Ischemia) 09/2005
1	Nervous System Diseases (Neurological Disorders) 12/2004
1	Acute Coronary Syndrome 01/2004
1	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 01/2003

Drug/Important Bio-Agent (IBA)

4	Biomarkers (Surrogate Marker)IBA 11/2020 - 06/2011
4	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2020 - 05/2002
4	Warfarin (Coumadin)FDA LinkGeneric 08/2019 - 12/2004
3	AnticoagulantsIBA 08/2019 - 11/2002
3	danaparoid (Orgaran)FDA Link 10/2011 - 11/2006
2	Donepezil (Aricept)FDA LinkGeneric 05/2011 - 07/2010
2	Peptides (Polypeptides)IBA 08/2006 - 12/2005
2	Caspase 3 (Caspase-3)IBA 08/2006 - 12/2005
2	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 03/2006 - 09/2005
2	salicylhydroxamic acid (SHAM)IBA 12/2005 - 09/2005
2	Proteins (Proteins, Gene)FDA Link 09/2005 - 07/2003
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 03/2021
1	Cilostazol (Pletal)FDA LinkGeneric 03/2021
1	oxidized low density lipoproteinIBA 12/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019
1	CytokinesIBA 01/2019
1	LDL Lipoproteins (beta Lipoproteins)IBA 02/2017
1	Anesthetics (Anesthetic Agents)IBA 07/2016
1	Aluminum Oxide (Sapphire)IBA 03/2015
1	Hemin (Panhematin)FDA Link 10/2014
1	Mitochondrial DNA (mtDNA)IBA 03/2013
1	Amino Acids FDA Link 01/2013
1	Cysteine (L-Cysteine)FDA Link 01/2013
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 10/2011
1	P-2 (P 2)IBA 10/2011
1	Integrin alpha2IBA 01/2008
1	Factor VIIa (Activated Factor VII)IBA 08/2007
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 04/2007
1	N-Methylaspartate (NMDA)IBA 12/2005
1	NMDA receptor A1IBA 12/2005
1	NestinIBA 09/2005
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 09/2005
1	recombinant FVIIa (rFVIIa)FDA Link 12/2004
1	Platelet Membrane GlycoproteinsIBA 01/2004
1	Platelet Membrane Glycoprotein IIbIBA 01/2004
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 01/2004
1	Hemostatics (Antihemorrhagics)IBA 07/2003
1	DNA (Deoxyribonucleic Acid)IBA 01/2002

Therapy/Procedure

46	Carotid Endarterectomy 01/2022 - 07/2001
42	Endarterectomy (Thromboendarterectomy) 01/2022 - 07/2001
24	Therapeutics 01/2022 - 02/2003
10	Stents 01/2021 - 12/2004
6	Vascular Surgical Procedures 01/2013 - 02/2011
2	Drug Therapy (Chemotherapy) 08/2019 - 07/2010
1	Ambulatory Care (Outpatient Care) 01/2020
1	Thrombectomy 01/2020
1	Injections 01/2020
1	Local Anesthesia 12/2019
1	Aftercare (After-Treatment) 01/2019
1	Secondary Prevention 01/2014
1	Time-to-Treatment 05/2010
1	Craniotomy 12/2004
1	Mechanical Ventilators (Ventilator) 01/2003